I have PCOS, and it has never stopped me from hooking up. Sure, I have many of the symptoms of PCOS . . . weight issues, acne . . . I just make my flaws known to potential partners in the beginning.
I tell them that I am a big girl and that I have acne. Most of them ask why, and I explain PCOS to them. Most guys forget about the flaws and get really happy about the not being able to get pregnant thing!