We were sort of 'stalked' by a couple last weekend.
Mind you it wasn't too weird, but we were most definitely their prey. It started when he asked me to guard his wife while he went to the bathroom. I figured they were newbies and I looked safe or the like, but in conversation it turns out they weren't newbies so why would he need me to guard his wife? She wasn't drunk and the club is pretty safe seeming. Ok, well he comes back, and then says to guard her more while he goes to I don't know where. I'd been gone from my group for a while and after a bit excused myself after a few more minutes to rejoin my wife and the group at the other side of the bar (my wife thought I was only getting a drink after all).
Well when I get back to the group there is no room to stand next to my wife and I put my arm around a long time friend of ours and I see the other couple looking our direction. Not a big deal of course.
Fast forward about an hour or so and my friend and I are dancing and its semi crowded on the dance floor. While we are up there the stalking couple (not that I knew it at the time) starts to dance as well (they didn't get on the floor till after we did) and with the volume of the music they must not have known how loud they were while talking and I hear them make brief plans to split us up and dance. Now again, nothing 'weird' about it, though I'm not sure you want to let your target know they are a target

I'm now pretty sure the whole 'guard my wife thing' was a set up of course too.
A couple of women fell over on the dance floor which broke up our dance early and we rejoined the group again, never really having exchanged much with this couple beyond a brief dance and a few words. We had no plans in playing with them as we were with a group of old friends and new ones who all came together.
It did get a little odd in the play rooms. We were in a private room but we had 9 people in there at one point, and at 1am with as much drinking as we had done people had to make a run to the bathroom now and then so the door didn't always stay locked. The male of the stalking couple sticks his head in the door and just kinda gives a hard stare around the room, he pulls his head back and another guy does the same. I tell them its occupied and lock the door. Some time later we are just about done and a couple had left earlier (so the door was unlocked again, sigh) This time he does the same thing looking in and kinda pushes his wife into the room too. Luckily we were finishing up so we all left at that point without having to say get out.
Now outside of the swinging etiquette fopaw (at this club closed door means stay out) and the fact that this guy was already told we were occupied once, do others pick out couples early in a party and attempt to 'get with them' in a calculated manner or are you more likely to just go with the flow and see what develops? Personally I have no problem with being 'singled out' we just weren't interested and the end got a bit creepy.